Table 1.
Biopsy outcome: Normal | Biopsy outcome: Abnormal | |||||
---|---|---|---|---|---|---|
WBC range (×1000 cells/µL)a | Number in range | Number within genotype-informed rangeb | Percentage within range | Number in range | Number within genotype-informed rangeb | Percentage within range |
>3.5–4.0 | 10 | 10 | 100 | 3 | 3 | 100 |
>3.0–3.5 | 13 | 9 | 69.2 | 6 | 0 | 0 |
>2.5–3.0 | 18 | 1 | 5.6 | 2 | 0 | 0 |
0–2.5 | 18 | 0 | 0 | 10 | 0 | 0 |
aWBC count at the time of bone marrow biopsy.
bIndividuals whose WBC count fell above the 2.5th percentile of the distribution of WBC counts observed among individuals in the WBC cohort whose PGSWBC value was within 0.2 standard deviations. WBC count distributions were constructed based on the lowest observed WBC count among an individual.