Table 1.
Clinical Characteristics
| Men |
Women |
|||||
|---|---|---|---|---|---|---|
| Depression (−) (n = 2,271,247) |
Depression (+) (n = 99,739) |
P Value | Depression (−) (n = 1,676,376) |
Depression (+) (n = 78,358) |
P Value | |
| Age, y | 44 (36, 52) | 44 (38, 51) | <0.001 | 44 (36, 52) | 44 (36, 51) | 0.28 |
| Body mass index, kg/m2 | 23.2 (21.2, 25.6) | 23.5 (21.4, 26.1) | <0.001 | 21 (19.2, 23.4) | 21.1 (19.2, 23.8) | <0.001 |
| Obesity | 697,363 (30.7) | 34,300 (34.4) | <0.001 | 268,756 (16.0) | 14,691 (18.7) | <0.001 |
| Systolic blood pressure, mm Hg | 121 (112, 130) | 120 (111, 129) | <0.001 | 112 (102, 124) | 111 (102, 123) | <0.001 |
| Diastolic blood pressure, mm Hg | 75 (68, 83) | 76 (68, 83) | <0.001 | 69 (62, 77) | 69 (62, 77) | <0.001 |
| Hypertension | 500,541 (22.0) | 24,181 (24.2) | <0.001 | 211,269 (12.6) | 11,629 (14.8) | <0.001 |
| Diabetes mellitus | 129,122 (5.7) | 6,310 (6.3) | <0.001 | 34,442 (2.1) | 1,981 (2.5) | <0.001 |
| Dyslipidemia | 1,060,129 (46.7) | 53,032 (53.2) | <0.001 | 473,625 (28.3) | 26,597 (33.9) | <0.001 |
| Cigarette smoking | 809,137 (35.6) | 32,842 (32.9) | <0.001 | 189,557 (11.3) | 10,893 (13.9) | <0.001 |
| Alcohol consumption | 673,643 (29.7) | 24,837 (24.9) | <0.001 | 205,983 (12.3) | 8,307 (10.6) | <0.001 |
| Physical inactivity | 1,153,587 (50.8) | 54,777 (54.9) | <0.001 | 875,698 (52.2) | 43,256 (55.2) | <0.001 |
| Fast plasma glucose, mg/dL | 93 (87, 101) | 93 (87, 101) | <0.001 | 89 (84, 95) | 89 (84, 95) | <0.001 |
| Low-density lipoprotein cholesterol, mg/dL | 121 (101, 143) | 124 (103, 146) | <0.001 | 113 (94, 136) | 116 (96, 138) | <0.001 |
| High-density lipoprotein cholesterol, mg/dL | 56 (48, 66) | 56 (47, 66) | <0.001 | 70 (60, 81) | 69 (59, 81) | <0.001 |
| Triglycerides, mg/dL | 95 (66, 142) | 103 (70, 155) | <0.001 | 64 (48, 90) | 70 (51, 101) | <0.001 |
Values are median (Q1, Q3) or n (%).