Table 1.
Univariable analysis of the association of demographic features and visible pores in the Lamina Cribrosa among POAAGG glaucoma cases (n = 2943 eyes).
| n | Visible Pores in the Lamina Cribrosa (n = 2117 Eyes) | RR (95%CI) | p-Value | ||
|---|---|---|---|---|---|
| Age (years) | ≤60 | 682 | 511 (74.9%) | Ref | 0.08 |
| (60, 70] | 836 | 618 (73.9%) | 0.99 (0.92, 1.06) | ||
| (70, 80] | 880 | 606 (68.9%) | 0.92 (0.85, 0.99) | ||
| ≥80 | 545 | 382 (70.1%) | 0.94 (0.86, 1.02) | ||
| Sex | Male | 1213 | 890 (73.4%) | Ref | 0.22 |
| Female | 1730 | 1227 (70.9%) | 0.97 (0.92, 1.02) | ||
| Body mass index | <25 | 689 | 502 (72.9%) | 0.97 (0.91, 1.04) | 0.048 |
| 25–30 | 979 | 732 (74.8%) | Ref | ||
| ≥30 | 1275 | 883 (69.3%) | 0.93 (0.87, 0.99) | ||
| Diabetes | No | 1794 | 1312 (73.1%) | Ref | 0.14 |
| Yes | 1143 | 801 (70.1%) | 0.96 (0.91, 1.01) | ||
| Missing | 6 | 4 | |||
| q0 (per 0.1 increase in q0) | 1807 | 1278 (70.7%) | 0.97 (0.95,0.99) | 0.006 | |
| Hypertension | No | 641 | 490 (76.4%) | Ref | 0.01 |
| Yes | 2296 | 1623 (70.7%) | 0.92 (0.87, 0.98) | ||
| Missing | 6 | 4 | |||
| Family history of glaucoma | No | 1191 | 847 (71.1%) | Ref | 0.63 |
| Yes | 1599 | 1153 (72.1%) | 1.01 (0.96, 1.07) | ||
| Missing | 153 | 117 | |||
| Alcohol use | No | 1556 | 1114 (71.6%) | Ref | 0.79 |
| Yes | 1346 | 971 (72.1%) | 1.01 (0.95, 1.06) | ||
| Missing | 41 | 32 | |||
| Tobacco use | No | 1339 | 982 (73.3%) | Ref | 0.19 |
| Yes | 1604 | 1135 (70.8%) | 0.96 (0.91, 1.02) | ||
| Previous glaucoma surgery | No | 2067 | 1497 (72.4%) | Ref | 0.43 |
| Yes | 868 | 614 (70.7%) | 0.98 (0.92, 1.04) | ||
| Missing | 8 | 6 | |||