Table 2.
Patients’ baseline characteristics according to the study arm
| QDOT-by-LAWT (n = 81) | CLOSE (n = 81) | Total patients (n = 162) | P-value | |
|---|---|---|---|---|
| Age (years) | 61.1 ± 10.6 | 63.1 ± 11.1 | 62.1 ± 10.9 | 0.19 |
| Male | 53 (65.4) | 49 (60.5) | 102 (63.0) | 0.62 |
| BMI (kg/m2) | 26.3 ± 4.2 | 27.0 ± 4.2 | 26.6 ± 4.2 | 0.32 |
| Hypertension | 28 (35.6) | 31 (38.3) | 59 (36.4) | 0.51 |
| Dyslipidaemia | 15 (18.5) | 18 (22.2) | 33 (40.7) | 0.56 |
| Smoke history | 11 (13.6) | 9 (11.1) | 20 (12.3) | 0.81 |
| Type 2 diabetes | 5 (6.2) | 5 (6.2) | 10 (6.2) | 0.99 |
| LVEF | 60.8 ± 7.4 | 61.1 ± 5.6 | 61.0 ± 6.6 | 0.68 |
| LA diameter (mm) | 38.5 ± 5.3 | 38.4 ± 5.9 | 38.5 ± 5.6 | 0.89 |
| CHA2DS2-VASc score | 1.0 (1.0–2.0) | 1.0 (1.0–3.0) | 1.0 (1.0–3.0) | 0.13 |
| HAS-BLED score | 1.0 (0.0–1.0) | 1.0 (0.0–1.0) | 1.0 (0.0–1.0) | 0.79 |
| Underlying cardiomyopathy | 0.38 | |||
| None | 66 (81.5) | 66 (81.5) | 132 (81.5) | |
| Hypertensive | 4 (4.9) | 9 (11.12) | 13 (8.0) | |
| Ischaemic | 4 (4.9) | 2 (2.5) | 6 (3.7) | |
| Valvular | 3 (3.7) | 1 (1.2) | 4 (2.5) | |
| Hypertrophic | 1 (1.2) | 1 (1.2) | 2 (1.2) | |
| Other | 3 (3.7) | 2 (2.5) | 5 (3.1) |
Results are reported as n (%) for categorical variables and median (inter-quartile range) or mean ± standard deviation for continuous variables.
BMI, body mass index; LA, left atrium; LVEF, left ventricle ejection fraction; PVs, pulmonary veins.