Table 2.
Subgroup analysis of the source of heterogeneity in meta-analysis of randomized controlled trials comparing efficacy of music therapy with inactive control groups.
| Characteristics | Number of studies | Sample size | Heterogeneity [I2], % (P) | Standardized Mean Difference (95%CI) | Q | P | |
|---|---|---|---|---|---|---|---|
| Experimental group | Control group | ||||||
| Participants | |||||||
| Medically ill patients | 4 | 143 | 141 | 96.1(<0.001) | −2.04(−3.11,−0.96) | ||
| Psychiatric patients | 2 | 29 | 31 | 76.2(0.040) | −1.26(−2.70,0.18) | ||
| Veterans | 1 | 25 | 15 | Not applicable | −0.70(−1.36,−0.04) | 4.37 | 0.113 |
| Sample | |||||||
| Males + females | 4 | 113 | 102 | 85.1(<0.001) | −1.84(−2.82,−0.85) | ||
| Females only | 3 | 84 | 85 | 93.8(<0.001) | −1.39(−2.83,0.06) | 0.26 | 0.612 |
| Mean age | |||||||
| < 40 years | 4 | 111 | 109 | 86.5(<0.001) | −1.83(−2.83,−0.83) | ||
| > 40 years | 3 | 86 | 78 | 93.6(<0.001) | −1.40(−2.84,0.04) | 0.23 | 0.630 |
| Diagnostic criteria of PTSD | |||||||
| DSM | 2 | 35 | 35 | 28.7(0.240) | −2.78(−3.46,−2.10) | ||
| DSM + ICD | 1 | 21 | 23 | Not applicable | −0.63(−1.24,−0.02) | ||
| Not reported | 3 | 116 | 114 | 91.8(<0.001) | −1.72(−2.95,−0.50) | ||
| ICD | 1 | 25 | 15 | Not applicable | −0.70(−1.36,−0.04) | 18.60 | <0.001 |
| Music therapy | |||||||
| Led by music therapists | 4 | 81 | 73 | 89.1(<0.001) | −1.58(−2.75,−0.40) | ||
| Music listening only | 3 | 116 | 114 | 91.8(<0.001) | −1.72(−2.95,−0.50) | 0.030 | 0.866 |
| Treatment duration | |||||||
| 2–4 months | 3 | 75 | 75 | 0.0(0.49) | −2.83(−3.29,−2.36) | ||
| <2 months | 4 | 122 | 112 | 73.6(0.038) | −0.95(−1.47,−0.42) | 27.79 | <0.001 |
| Treatment frequency | |||||||
| Daily | 3 | 116 | 114 | 92.3(<0.001) | −1.72(−2.95,−0.50) | ||
| Weekly or biweekly | 4 | 81 | 73 | 89.1(<0.001) | −1.58(−2.75,−0.40) | 0.030 | 0.866 |
| Intervention of the control group | |||||||
| Care as usual alone | 4 | 143 | 141 | 91.1(<0.001) | −2.04(−3.11,−0.96) | ||
| Waitlist + care as usual | 3 | 54 | 46 | 54.7(0.110) | −0.95(−1.63,−0.26) | 2.79 | 0.095 |
Note: DSM, Diagnostic & Statistical Manual of Mental Disorders; ICD, International Classification of Diseases; NR, not reported