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. Author manuscript; available in PMC: 2024 Apr 23.
Published in final edited form as: Nat Neurosci. 2023 Jul 31;26(9):1529–1540. doi: 10.1038/s41593-023-01397-2

Extended Data Fig. 10. Suppressing MPOA Vgat neurons in male mice, local administration of estrogen in MPOA and local administration of an estrogen receptor antagonist in MPOA.

Extended Data Fig. 10.

a-h, Local administration of estradiol (E2) (or vehicle) in MPOA following the HW procedure in female mice. N=8 animals for each group. Mean ± s.d. Statistics: ***P = 0.0002 (b), ****P < 0.0001 (c), ****P < 0.0001 (d), **P = 0.0011 (e), ***P = 0.0004 (f), ***P = 0.0005 (g), ****P < 0.0001 (h), two-tailed Mann-Whitney test, n = 9 mice in each group. i-p, I.p. administration of estradiol (E2) and local administration of estrogen receptor antagonist (ICI 182,780) (or vehicle) in MPOA following the HW procedure in female mice. n = 9 mice in each group, Mean ± s.d. Statistics: **P = 0.0097 (j), *P = 0.0379 (k), *P = 0.0362 (l), ***P = 0.0009 (m), *P = 0.0101 (n), **P = 0.0068 (o), ***P = 0.0002 (p), two-tailed Mann-Whitney test..