Table 1.
Overall patient (N = 11,883) characteristics stratified according to survival time (time of SAPC therapy from start to death)
| Parameter | Category | Survival time (from SAPC start to death) | p value | ||
|---|---|---|---|---|---|
| <7 days, N (%)/Med (IQR) | 7–100 days, N (%)/Med (IQR) | >100 days, N (%)/Med (IQR) | |||
| Patients | 2,464 (100) | 7,085 (100) | 2,334 (100) | ||
| Center | A | 466 (18.9) | 1,265 (17.9) | 491 (21) | <0.001 |
| B | 390 (15.8) | 914 (12.9) | 308 (13.2) | ||
| C | 983 (39.9) | 3,263 (46.1) | 1,087 (46.6) | ||
| D | 598 (24.3) | 1,548 (21.8) | 425 (18.2) | ||
| E | 27 (1.1) | 95 (1.3) | 23 (1) | ||
| Age, years | Med (IQR) | 80 (72–87) | 77 (66–83) | 74 (63–81) | <0.001 |
| Age group | <56 years | 129 (5.2) | 668 (9.4) | 287 (12.3) | <0.001 |
| >75 years | 1,629 (66.1) | 3,842 (54.2) | 1,073 (46) | ||
| 56–65 years | 254 (10.3) | 989 (14) | 438 (18.8) | ||
| 66–75 years | 452 (18.3) | 1,586 (22.4) | 536 (23) | ||
| Gender | Female | 1,199 (48.7) | 3,332 (47) | 1,133 (48.5) | 0.240 |
| Male | 1,265 (51.3) | 3,753 (53) | 1,201 (51.5) | ||
| Leading symptoms | Pain | 1,487 (60.3) | 4,518 (63.8) | 1,422 (60.9) | 0.002 |
| Urology | 214 (8.7) | 714 (10.1) | 293 (12.6) | <0.001 | |
| Cardiorespiratory | 1,017 (41.3) | 2,439 (34.4) | 769 (32.9) | <0.001 | |
| Gastrointestinal | 630 (25.6) | 2,576 (36.4) | 825 (35.3) | <0.001 | |
| Wound | 169 (6.9) | 525 (7.4) | 195 (8.4) | 0.135 | |
| Neuropsychiatric | 1,289 (52.3) | 3,463 (48.9) | 1,104 (47.3) | 0.001 | |
| Other severe symptoms | 1,793 (72.8) | 4,817 (68) | 1,565 (67.1) | <0.001 | |
| Survival time, days | Med (IQR) | 3 (2–5) | 25 (13–49) | 209 (139–369) | <0.001 |
| THC | No | 2,446 (99.3) | 6,875 (97) | 2,234 (95.7) | <0.001 |
| Yes | 18 (0.7) | 210 (3) | 100 (4.3) | ||
| THC dose, mg/day | Med (IQR) | 2.4 (2.4–4.8) | 4.7 (2.4–7.2) | 6.8 (3.2–9.6) | <0.001 |
| THC dose | ≤4.7 mg/day | 13 (72.2) | 105 (50) | 32 (32) | <0.001 |
| >4.7 mg/day | 5 (27.8) | 105 (50) | 68 (68) | ||
Med, median; IQR, interquartile range; N, number; THC, tetrahydrocannabinol.