Table 3. Differentially expressed proteins without previously known association to thrombosis in Lemierre's syndrome (LS; n = 8) versus other severe infections ( n = 15) .
Proteins without known anti- or prothrombotic effects | Uniprot ID | Fold change LS vs. other severe infections | q |
---|---|---|---|
Polymeric Ig receptor | P01833 | 4.7 | 0.038 |
Golgi membrane protein 1 | Q8NBJ4 | 4.6 | 0.01 |
Oncoprotein-induced transcript 3 protein | Q8WWZ8 | 3.9 | 0.022 |
Leukocyte Ig-like receptor subfamily A member 3 | Q8N6C8 | 3.9 | 0.01 |
Alpha-1-antichymotrypsin | P01011 | 2.4 | 0.015 |
Phosphatidylinositol-glycan-specific phospholipase D | P80108 | 0.30 | 0.010 |
Note: Statistically significant differences were determined by independent samples t -test with Benjamini–Hochberg multiple comparison correction used ( q < 0.05) and log2 fold change of at least 1.