Table 2.

Cox regression. Effect of demographic, tumor and surgical variables on overall survival

	B (ET)	Wald	HR (IC 95%)	p-value
Age (≥ 45 vs. < 45)	0.63 (0.56)	1.29	1.88 (0.63–5.57)	0.256
Smoker (Yes vs. No)	0.31 (0.47)	0.43	1.36 (0.54–3.39)	0.512
Drinkers (Yes vs No)	0.07 (0.43)	0.03	1.07 (0.46–2.49)	0.874
Margin status
Free > 5 mm	1
Next < 5 mm	0.79 (0.36)	4.83	2.20 (1.09–4.43)	0.028
Affected	1.35 (0.46)	8.52	3.86 (1.56–9.57)	0.004
Size (T3T4 vs. T1T2)	0.27 (0.78)	0.12	1.31 (0.29–6.03)	0.729
N0/N + (N + vs. N0)	0.73 (0.84)	0.75	2.07 (0.40–10.73)	0.388
Stage (Advanced vs. Initial)	0.32 (0.86)	0.13	1.37 (0.25–7.44)	0.715
Extracapsular invasion (Yes vs. No)	−0.23 (0.57)	0.16	0.80 (0.26–2.45)	0.691
Lymphadenectomy (Yes vs. No)	−1.88 (0.52)	12.99	0.15 (0.06–0.42)	< 0.001
Invasion (Yes vs. No)	0.55 (0.40)	1.95	1.74 (0.80–3.78)	0.163

B, regression coefficient; ET, standard error; HR, Hazard ratio; CI, confidence interval

The bold values are statistically significant.