FIG. 6.

Sequence of a vector-cellular junction identified by Alu-PCR from human NT neurons transduced with the CMVβ-gal rAAV vector. (a) The vector portion of the junction includes the 5′ end of the CMV IE promoter (open box) and some AAV sequences (underlined) containing a partial AAV ITR. The cellular sequence includes a fragment with 98% homology to a human DNA sequence on chromosome 9q34 (dashed underlined). The actual sequence in the shaded box is shown in panel b. The arrows in panels a and b point to the site of the vector-cellular junction.