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. 2024 Apr 10;11:1325128. doi: 10.3389/fmed.2024.1325128

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Copyright © 2024 Dogan, Watkins, Ingram, Moore, Rucker, Gower, Eason, Bhalla, Talwar, Nezakatgoo, Eymard, Helmick, Vanatta, Bajwa, Kuscu and Kuscu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Risk Variants of the APOL1 gene (A) Graphical representation of the APOL1 protein showing its domains and the location of the G1 and G2 variants in the SRA domain (B) Representation of the base changes at individual SNP and deletion sites. DNA structures for homozygous wild-type (2–0), heterozygous (1–1), and homozygous SNP/deletion (0–2) variants are shown in three panels. (C) Predicted results of qPCR analysis using our probe-independent real-time quantitative PCR approach. This figure has been generated with Biorender program.