Table 2.
The MR results between GM taxa and aneurysm.
| Exposure | Outcome | Methods | OR (95%CI) | Pval | Heterogeneity | Horizontal pleiotropy | F-statistic (min) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cochran’s Q | Pval | PRESSO global test | Pval | Egger (intercept) | Pval | ||||||
| Phylum.Firmicutes.id.1672 | AAA | IVW (fixed) | 0.620 (0.475, 0.809) | 4.3 × 10−4 | 8.872 | 0.783 | 10.366 | 0.800 | −0.012 | 0.695 | 19.587 |
| Weighted mode | 0.597 (0.347, 1.027) | 0.063 | |||||||||
| Weighted median | 0.632 (0.437, 0.913) | 0.015 | |||||||||
| MR-Egger (slope) | 0.735 (0.301, 1.795) | 0.499 | |||||||||
| MR-PRESSO | 0.620 (0.498, 0.773) | 9.26 × 10−4 | |||||||||
| Class.Lentisphaeria.id.2250 | AAA | IVW (fixed) | 0.746 (0.624, 0.891) | 1.25 × 10−3 | 3.992 | 0.858 | 5.089 | 0.880 | −0.037 | 0.438 | 20.223 |
| Weighted mode | 0.884 (0.649, 1.204) | 0.435 | |||||||||
| Weighted median | 0.749 (0.592, 0.947) | 0.016 | |||||||||
| MR-Egger (slope) | 0.960 (0.495, 1.860) | 0.903 | |||||||||
| MR-PRESSO | 0.746 (0.658, 0.846) | 0.002 | |||||||||
| Order.Victivallales.id.2254 | AAA | IVW (fixed) | 0.746 (0.624, 0.891) | 1.25 × 10−3 | 3.992 | 0.858 | 5.089 | 0.880 | −0.037 | 0.438 | 20.223 |
| Weighted mode | 0.884 (0.649, 1.204) | 0.435 | |||||||||
| Weighted median | 0.749 (0.592, 0.947) | 0.016 | |||||||||
| MR-Egger (slope) | 0.960 (0.495, 1.860) | 0.903 | |||||||||
| MR-PRESSO | 0.746 (0.658, 0.846) | 0.002 | |||||||||
AAA, abdominal aortic aneurysm.