Skip to main content
. 2024 Mar 28;21(3):340–348. doi: 10.26599/1671-5411.2024.03.006

Table 2. Sensitivity analysis result with Cochran’s Q test and MR-Egger intercept.

Outcome Cochran Q test MR-Egger
Q value P-value Intercept P-value
Cerebrovascular diseases
 Stroke (MRC-IEU) 49.3269 0.8357 –0.0001 0.5683
 Stroke (UKBB) 56.1915 0.7156 –0.0002 0.9716
 Ischemic stroke (UKBB) 51.3436 0.8308 0.0018 0.7910
 Ischemic stroke (ISGC) 39.1764 0.7161 -0.0019 0.8819
 Ischemic stroke (small-vessel) 50.3819 0.6866 –0.0062 0.6467
 Lacunar stroke 42.2953 0.9791 –0.0042 0.7360
 Cardioembolic stroke 36.9359 0.7306 0.0115 0.6678
Heart diseases
 Essential (primary) hypertension (MRC-IEU) 48.1453 0.5877 -0.0005 0.2478
 Essential (primary) hypertension (Neale Lab) 61.6693 0.6610 0.0000 0.9620
 Atherosclerotic heart disease 46.8189 0.8533 0.0000 0.8134
 Heart attack / Myocardial infarction (MRC-IEU) 52.5110 0.6440 –0.0001 0.4830
 Heart attack / Myocardial infarction (Neale Lab) 44.6690 0.8618 0.0000 0.9977
 Myocardial infarction 61.5354 0.5287 –0.0047 0.4706
 Acute myocardial infarction 54.2596 0.6845 -0.0002 0.1093
 Atrial fibrillation and flutter (secondary) 45.7735 0.8962 –0.0004 0.0130
 Atrial fibrillation and flutter (main) 58.1225 0.7720 0.0000 0.7590
 Heart arrhythmia 49.3248 0.3417 -0.0002 0.2857
 Unstable angina (MRC-IEU) 25.5225 0.9228 –0.0002 0.2593
 Unstable angina (Sakaue S et al. ebi-a-GCST90018932) 45.3716 0.9541 -0.0067 0.4290
 Unstable angina (Sakaue S et al. ebi-a-GCST90018712) 46.3483 0.6587 0.0051 0.7586
 Angina pectoris (MRC-IEU) 52.1029 0.6589 0.0000 0.9834
 Angina pectoris (Neale Lab) 49.6316 0.9065 0.0000 0.8159
Vessel diseases
 Peripheral artery disease 54.4815 0.8208 0.0000 0.5723
Venous thromboembolism 47.6172 0.9251 0.0000 0.8530