Table 2.
Interaction between heredity and environmental factors in the development of myopia.
| Genetic Factors | Environment Factors | First Author | Reference |
|---|---|---|---|
| Heredity | Near work (homework time and staring at an electronic screen) | Zhang, X. | [109] |
| High genetic risk score (high GRS) | Near work and Outdoor activities | Enthoven, C.A. | [110] |
| rs7829127 in ZMAT4 | Near work | Fan, Q. | [112] |
| GRS | Time of near work | Liu, S. X. | [113] |
| APLP2 rs188663068 | Time spent reading | Tkatchenko, A.V. | [115] |
| Genetic predisposition | Education | Verhoeven, V.J. | [117] |
| SHISA6-DNAH9: rs2969180 A allele, GJD2: rs524952 A allele, ZMAT4-SFRP1: rs2137277 A allele | Education | Fan, Q. | [118] |
| GJD2, RBFOX1, LAMA2, KCNQ5, LRRC4C | Education | Clark, R | [120] |