Figure 5.

Identification of differentially expressed proteins in the injured brain and expression of IL-3 after hpcMSC treatment.

(A) Protein chip profiles of differentially expressed proteins in the right cortex and hippocampus between sham and HI groups. Red represents high expression and green represents low expression. (B) The intersection of differentially expressed proteins from two tissues. (C) The fold change of three identified proteins with high fold change. (D) The mRNA expression of IL-3 in the cortex and hippocampus in sham, HI, NS and hpcMSCs transplantation groups. All data are presented as the primary data (C) or mean ± SD (D) (n = 5/group). *P < 0.05 (one-way analysis of variance followed by Tukey's post hoc test). HI: Hypoxia-ischemia; hpcMSC: human placental chorionic derived mesenchymal stem cell; IL-3: interleukin-3; NS: normal saline.