Figure 8.

Activation of JNK signaling is vital for RSA treatment via JPT2. A) Pregnant mice received JNK inhibitor (JNK‐IN‐8, 20 mg kg⁻¹) injections on days 8.5 and 10.5 of gestation, mice were euthanized on day 11.5 of gestation, and embryo resorption rates were calculated (each group: n = 8). Scale bar, 0.5 cm. B) Immunostaining ACKR3 at the placental interface of mice (each group: n = 8). Scale bar, 50 µm. C) Immunostaining of IL‐6R in the decidual macrophages of mice (each group: n = 8). Scale bar, 50 µm.