Figure 8.

Analysis of Pt(II) complexes incubated with HP-DNA was performed by dPAGE. 1-click, 2-click, and 3-click represent complexes that were first incubated with HP for 24 h followed by click reaction with Alexa-647 DBCO for an additional 24 h. Control complexes were incubated for 48 h with HP without click reaction. All samples were purified by spin column prior to dPAGE analysis. Gray: DNA stained with SYBR gold (539 nm emission wavelength), red: DNA-Pt-647 DBCO complex (671 emission wavelength).