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. 2024 Apr 24;22:382. doi: 10.1186/s12967-024-05199-3

Table 1.

Groups of collagen receptors

Receptors Expression Function upon binding collagen
Integrins All cells Regulation of cell adhesion [29]
Discoidin domain Receptor family Epithelial cells and mesenchymal cells Regulation of cell migration, differentiation, proliferation, survival, ECM remodeling [30]
Mannose receptor family Macrophages and fibroblasts Endocytosis of collagen for lysomal degradation [31]
Glycoprotein VI Platelets Platelet activation [32]
Osteoclast-associated receptor Osteoclasts, myeloid cells Osteoclast differentiation, Monocyte survival [33]
Leukocyte Associated Immunoglobulin Like Receptor 1 Immune cells Inhibition of immune cell activity [34]