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The agent-specific reported adverse effects associated with HDACis
| HDACi | Specific adverse effects reported in clinical trials |
|---|---|
| Panobinostat | Cardiac ischaemia, haemorrhage |
| Vorinostat | Hyper-glycaemia, pulmonary embolism, deep vein thrombosis |
| Belinostat | Infections, tumour lysis syndrome |
| Romidepsin | Infections, tumour lysis syndrome |
| Chidamide | Raised creatine phosphokinase levels, pericardial effusion |
