Fig. 7.

Inhibition of Mas or Nrf2 abolished the effects of AVE0991 after ICH. A Representative western blot bands. B–E quantitative analyses of p-Akt/Akt, Nrf2, iNOS, and CD163 at 3 days after ICH. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham; ^#P < 0.05, ^##P < 0.01 vs. ICH + Vehicle; ^@P < 0.05, ^@@P < 0.05 vs. ICH + AVE + A779. F Representative Western blot bands. G–I Quantitative analyses of Nrf2, iNOS, and CD163 at 3 days after ICH. *P < 0.05, **P < 0.01, ***P < 0.001 vs. Sham; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. ICH + Vehicle; ^@P < 0.05, ^@@P < 0.05 vs. ICH + AVE + ML385. Data was represented as mean ± SD, n = 6/group. Veh, Vehicle; AVE, AVE0991