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. 2024 Mar 19;15(16):6115–6121. doi: 10.1039/d4sc00808a

Scope of donor molecules 2 a.

graphic file with name d4sc00808a-u3.jpg
Entry 2 Ar2 R4 R5 3 Yield of 3 b (%)
1c 2b 4-CF3C6H4 H H 3n 18 (21)c
2 2c 4-BrC6H4 H H 3o 54 (50)c
3 2d Ph Me H 3p 62
4 2e Ph Me Me 3q NRd
a

Unless otherwise specified, all reactions were carried out using 0.1 mmol of 1, 1.0 mmol (10 equiv.) of 2, 10 μmol (10 mol%) of AgNTf2, 20 μmol (20 mol%) of P(4-CF3C6H4)3, and 5 equiv. of TFA in 1,2-dichloroethane (1 mL: 0.1 M of 1) at 50 °C for 1 h.

b

Isolated yield.

c

The reaction was conducted for 2 h.

d

NR: no reaction.