Scope of donor molecules 2 a.
| ||||||
|---|---|---|---|---|---|---|
| Entry | 2 | Ar2 | R4 | R5 | 3 | Yield of 3 b (%) |
| 1c | 2b | 4-CF3C6H4 | H | H | 3n | 18 (21)c |
| 2 | 2c | 4-BrC6H4 | H | H | 3o | 54 (50)c |
| 3 | 2d | Ph | Me | H | 3p | 62 |
| 4 | 2e | Ph | Me | Me | 3q | NRd |
Unless otherwise specified, all reactions were carried out using 0.1 mmol of 1, 1.0 mmol (10 equiv.) of 2, 10 μmol (10 mol%) of AgNTf2, 20 μmol (20 mol%) of P(4-CF3C6H4)3, and 5 equiv. of TFA in 1,2-dichloroethane (1 mL: 0.1 M of 1) at 50 °C for 1 h.
Isolated yield.
The reaction was conducted for 2 h.
NR: no reaction.