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. 2023 Jul 17;16(5):471–477. doi: 10.1136/jnis-2023-020435

Table 2.

Subgroup analysis: factors associated with missing clinical outcome data at 90 day follow-up despite complete baseline documentation in patients discharged from hospital alive.

Variable OR 95% CI P value
Older age 1.002 0.997 to 1.006 0.336
Female sex 1.069 0.962 to 1.187 0.215
Premorbid disability (mRS 3–5) 3.865 3.408 to 4.383 <0.001
Cardiovascular risk factors
 Arterial hypertension 1.125 0.990 to 1.279 0.071
 Diabetes mellitus 1.025 0.900 to 1.167 0.713
 Dyslipidemia 0.734 0.656 to 0.822 <0.001
 Atrial fibrillation 1.108 0.993 to 1.236 0.065
 Smoker (current) 1.087 0.936 to 1.263 0.274
Baseline medication
 Anticoagulation 1.160 1.021 to 1.319 0.023
 Platelet inhibition 1.047 0.927 to 1.183 0.459
Stroke characteristics
 Higher NIHSS on admission 1.012 1.004 to 1.019 0.002
Location of occlusion
 Carotid artery 1.129 1.000 to 1.275 0.050
 Anterior cerebral artery 0.838 0.582 to 1.206 0.341
 Middle cerebral artery M1 segment 1.120 1.007 to 1.246 0.036
 Middle cerebral artery M2 segment 1.005 0.888 to 1.138 0.933
 Posterior cerebral artery 0.984 0.723 to 1.338 0.918
 Vertebrobasilar 0.866 0.713 to 1.052 0.148
Stroke etiology
 Large artery atherosclerosis 1.521 1.359 to 1.702 <0.001
 Cardioembolism 0.961 0.865 to 1.067 0.454
 Dissection 0.655 0.417 to 1.028 0.006
 Other 0.804 0.615 to 1.051 0.110
 Undetermined 0.601 0.511 to 0.706 <0.001
Treatment characteristics
 Bridging intravenous thrombolysis 0.786 0.707 to 0.873 <0.001
 Primary admission at MT site 1.091 0.978 to 1.218 0.119
 Symptom onset/time to recognition-to-groin puncture (per 10 min) 1.001 1.000 to 1.003 0.038
 Door-to-groin puncture (per 10 min) 1.000 0.997 to 1.003 0.969
Outcome parameters
 Successful recanalization (TICI 2b-3) 0.929 0.792 to 1.089 0.361
 Good outcome at discharge (mRS 0–2) 0.821 0.734 to 0.918 <0.001
 Disabled at discharge (mRS 3–5) 1.218 1.089 to 1.362 <0.001
 Longer hospital stay per day 0.992 0.985 to 0.998 0.010
 Discharge to home or neurorehabilitation vs hospital or institutional care 1.754 1.558 to 1.976 <0.001

ORs, 95% CI, and corresponding P values resulting from univariate logistic regression determining association with missing clinical outcome (mRS at 90 day follow-up) following discharge from the treating hospital alive despite complete baseline documentation (age, sex, NIHSS on admission, intravenous thrombolysis, post-mechanical thrombectomy TICI, and mRS at discharge from treating hospital).

mRS, modified Rankin Scale; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; TICI, thrombolysis in cerebral infarction.