Table 2.
Subgroup analysis: factors associated with missing clinical outcome data at 90 day follow-up despite complete baseline documentation in patients discharged from hospital alive.
Variable | OR | 95% CI | P value |
Older age | 1.002 | 0.997 to 1.006 | 0.336 |
Female sex | 1.069 | 0.962 to 1.187 | 0.215 |
Premorbid disability (mRS 3–5) | 3.865 | 3.408 to 4.383 | <0.001 |
Cardiovascular risk factors | |||
Arterial hypertension | 1.125 | 0.990 to 1.279 | 0.071 |
Diabetes mellitus | 1.025 | 0.900 to 1.167 | 0.713 |
Dyslipidemia | 0.734 | 0.656 to 0.822 | <0.001 |
Atrial fibrillation | 1.108 | 0.993 to 1.236 | 0.065 |
Smoker (current) | 1.087 | 0.936 to 1.263 | 0.274 |
Baseline medication | |||
Anticoagulation | 1.160 | 1.021 to 1.319 | 0.023 |
Platelet inhibition | 1.047 | 0.927 to 1.183 | 0.459 |
Stroke characteristics | |||
Higher NIHSS on admission | 1.012 | 1.004 to 1.019 | 0.002 |
Location of occlusion | |||
Carotid artery | 1.129 | 1.000 to 1.275 | 0.050 |
Anterior cerebral artery | 0.838 | 0.582 to 1.206 | 0.341 |
Middle cerebral artery M1 segment | 1.120 | 1.007 to 1.246 | 0.036 |
Middle cerebral artery M2 segment | 1.005 | 0.888 to 1.138 | 0.933 |
Posterior cerebral artery | 0.984 | 0.723 to 1.338 | 0.918 |
Vertebrobasilar | 0.866 | 0.713 to 1.052 | 0.148 |
Stroke etiology | |||
Large artery atherosclerosis | 1.521 | 1.359 to 1.702 | <0.001 |
Cardioembolism | 0.961 | 0.865 to 1.067 | 0.454 |
Dissection | 0.655 | 0.417 to 1.028 | 0.006 |
Other | 0.804 | 0.615 to 1.051 | 0.110 |
Undetermined | 0.601 | 0.511 to 0.706 | <0.001 |
Treatment characteristics | |||
Bridging intravenous thrombolysis | 0.786 | 0.707 to 0.873 | <0.001 |
Primary admission at MT site | 1.091 | 0.978 to 1.218 | 0.119 |
Symptom onset/time to recognition-to-groin puncture (per 10 min) | 1.001 | 1.000 to 1.003 | 0.038 |
Door-to-groin puncture (per 10 min) | 1.000 | 0.997 to 1.003 | 0.969 |
Outcome parameters | |||
Successful recanalization (TICI 2b-3) | 0.929 | 0.792 to 1.089 | 0.361 |
Good outcome at discharge (mRS 0–2) | 0.821 | 0.734 to 0.918 | <0.001 |
Disabled at discharge (mRS 3–5) | 1.218 | 1.089 to 1.362 | <0.001 |
Longer hospital stay per day | 0.992 | 0.985 to 0.998 | 0.010 |
Discharge to home or neurorehabilitation vs hospital or institutional care | 1.754 | 1.558 to 1.976 | <0.001 |
ORs, 95% CI, and corresponding P values resulting from univariate logistic regression determining association with missing clinical outcome (mRS at 90 day follow-up) following discharge from the treating hospital alive despite complete baseline documentation (age, sex, NIHSS on admission, intravenous thrombolysis, post-mechanical thrombectomy TICI, and mRS at discharge from treating hospital).
mRS, modified Rankin Scale; MT, mechanical thrombectomy; NIHSS, National Institutes of Health Stroke Scale; TICI, thrombolysis in cerebral infarction.