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. 2023 Jul 11;28(12):5380–5389. doi: 10.1038/s41380-023-02166-0

Fig. 2. Neuropathological examination of brain tissue of IV:3 and VI:5.

Fig. 2

A Superior frontal gyrus of IV:3: AT8 stain. Many neurofibrillary tangles (arrow), as well as dystrophic neurites (arrowhead) and neuritic threads (asterisk) are detected. B Area striata of IV3: 4G8 stain. Small magnification to show the abundance of cerebral amyloid angiopathy (CAA, arrowhead) and senile plaques (arrow). C Superior temporal gyrus of IV:5 AT8 stain. Many neuritic threads (asterisk) and dystrophic neurites (arrowhead) affect the temporal cortex. Many neurons contain neurofibrillary tangles (arrow). D Parahippocampal gyrus of IV:5: 4G8 stain. Many large senile plaques (arrow), again in the presence of cerebral amyloid angiopathy (arrowhead).