Fig. 1. Significant increase in CD69+ T cells in the atherosclerotic plaque suggests an antigen-specific T cell response.
a, Experimental setup: single cells from PBMC and plaque samples were stained with fluorescently labelled antibodies and measured through flow cytometry. b, Flow cytometry analysis of CD69 expression on PBMC and plaque live CD4+ and CD8+ T cells. P values are depicted in the figure panels. Data are presented as mean values ± s.d. PBMC n = 58; plaque n = 61. Statistical analyses were performed using an unpaired Mann–Whitney t-test.