| HLA-A |
Antigen processing and presentation |
Crucial for immune response, presents peptide antigens to T cells |
| HLA-B |
Graft-versus-host disease, allograft rejection |
Plays a key role in immune system recognition, impacting graft compatibility |
| HLA-DRB1 |
Antigen processing and presentation |
Involved in presenting antigens to immune cells, crucial to the immune response |
| KIR2DL1 |
Natural killer cell-mediated cytotoxicity |
Regulates natural killer cell activity, important for immune surveillance |
| KIR2DL3 |
Natural killer cell-mediated cytotoxicity |
Influences the activity of natural killer cells, key in immune defense mechanisms |
| KIR2DS1 |
Natural killer cell-mediated cytotoxicity |
Affects natural killer cell function, important in immune system’s response |
| KIR2DS5 |
Natural killer cell-mediated cytotoxicity |
Modulates the activity of NK cells, playing a role in immune response |
| GHR |
Estrogen signalling pathway |
While primarily known for growth hormone receptor, may interact with estrogen signaling |
| SHC1 |
Estrogen signalling pathway |
Involved in signal transduction, potentially linking to estrogen pathways |
| SIRT1 |
Estrogen signalling pathway |
Known for roles in aging and metabolism, may have links to estrogen signaling |
