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[Preprint]. 2024 Apr 26:2024.04.17.589812. Originally published 2024 Apr 17. [Version 2] doi: 10.1101/2024.04.17.589812

Table 3b,

Transport Reaction Free Energy Changes, ΔG(effl) (kJ/mol), Efflux Version of Eq. (4) (Pi/Po = 1.00 || 1.05) effluxer reactions (I. II. or both, in Fig. 1) w/o metabolic substrates

KCC4 Ki+ + Cli + 500. H2Oi net
(0 || −0.13) + (−3.74 || −3.87) + 500(0.003 || −0.13) (1.5 || −65) = (−2.2 || −69)
MCT1 lactatei + H3Oi+ + 500 H2Oi
(6.99 || 6.86) + 500(0.003 || −0.13) (1.5 || −65) = (8.5 || −58)
NaDCl dicarboxylatei2− + 175 H2Oi + 2 Nai+
175(0.003 || −0.13) (0.53 || −23) + 2(14.5 || 14.3) (29 || 29) = (30 || 6.0)

All stoichiometries from reference (19). −ΔGper(infl) from Table 2. Em,oi = −91 mV