Figure 3. Somatic Mutations Detected by SearchLight DNA in Tumors from Dogs 1411 and 1410.

Mutations that are shared by both dogs are shown followed by those detected only in 1411 (bottom of left column) or 1410 (right column). These mutations represent primarily somatic SNVs and CNVs detected in 120 genes via the SearchLight DNA panel based on sequencing matched tumor and normal tissue for each dog. One germline sequence variant was detected in NF2 in Dog 1411, but was not shared by Dog 1410. Six genes bore similar somatic mutations in both cases whereas 27 genes bore mutations in only a single sibling’s tumor.