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. 2004 Oct 30;54(6):587–598. doi: 10.1007/s00262-004-0602-0

Table 1.

IFN-α response to NDV of human normal cells and tumor cells

Representative example IFN-α (pg/ml)a
Normal cells (adherent PBMCs)b Tumor cells (MCF-7)c
 +UV-inactivated NDV Ulster 86,431 <10
 +Live NDV Ulster 77,210 55
 Effects Independent on viral replication Dependent on viral replication
 IFN-α titers High Low

aCells (PBMCs or MCF-7) were coincubated for 3 days with 60 HU/107 cells of either live or UV-inactivated NDV, and then supernatants were tested by ELISA for IFN-α content

bThe major cell type producing IFN-α in PBMCs is the NIPC

cA human breast carcinoma cell line