Figure 2.

NGAL⁺ immune cells within PBMC populations and subsets tends to increase in the adaptive immune cells of subjects with CP. PBMCs from multicenter (PROCEED) discovery set (healthy controls, AP/RAP, and subjects with CP) collected during enrollment visit were analyzed by CyTOF. (a) Proportion of NGAL⁺ immune populations (b) and subpopulations. ^a P < 0.05 between control and CP; ^b P < 0.05 between AP/RAP and CP; ^c P < 0.05 between control and AP/RAP; ****P < 0.001. AP, acute pancreatitis; CP, chronic pancreatitis; CyTOF, mass cytometry by time-of-flight; NGAL, neutrophil gelatinase-associated lipocalin; PBMC, peripheral blood mononuclear cell; RAP, recurrent acute pancreatitis.