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Aspirin challenge caused a marked increase in permeability in all groups. (a) The 24-hour urinary lactulose (% excretion of oral dose) pre vs post aspirin (P value < 0.01, paired analysis). (b) The 24-hour urinary sucralose (% excretion of oral dose) pre vs post aspirin (P value < 0.01, paired analysis). (c) The 24-hour urinary sucralose/lactulose ratio pre vs post aspirin (P value < 0.01, paired analysis).
