Table 2.

Comparison of peri-operative features between pT1a and pT3a SRMs

Characteristic	pT1a* N = 1,671	pT3a* N = 166	p-value**
Mean age at nephrectomy	59 ± 11	62 ± 12	< 0.001
Male gender	1,079 (58.7%)	126 (76%)	0.003
BMI	30 ± 6.1	30.7 ± 6.2	0.2
Charlson comorbidity Index	0.82 ± 1.29	0.98 ± 1.4	0.1
Previously on active surveillance	106 (6.3%)	14 (8.4%)	0.3
R.E.N.A.L nephrometry score	6.83 ± 1.7	7.82 ± 1.9	< 0.001
Adverse radiologic features	259 (15.5%)	82 (49%)	< 0.001
Underwent radical nephrectomy	64 (3.8%)	35 (20%)	< 0.001
Surgery done via minimally invasive approach	703 (42.1%)	68 (41%)	0.8
Tumor size (max diameter) on pathology	2.5 ± 0.9	3.0 ± 0.9	< 0.001
Positive surgical margin	69 (4.1%)	16 (9.6%)	< 0.001
Tumor histology predominantly ccRCC	1,039 (62.2%)	110 (66%)	0.3
Nuclear grade			< 0.001
G1/2	786 (47%)	41 (25%)
G3/4	568 (34%)	104 (63%)
NA	317 (19%)	21 (13%)

^*Mean ± SD; n (%)

^**Student’s T-test; Pearson’s Chi-squared test