Table 3. Predictors of post-operative upstaging to pT3 on univariable and multivariable logistic regression modeling (LRM).
Univariable LRM | Multivariable LRM | |||||
---|---|---|---|---|---|---|
Characteristic | OR | 95% CI | p-value | OR | 95% CI* | p-value |
Mean age at nephrectomy | 1.03 | 1.02 - 1.05 | < 0.001 | 1.02 | 1.00 – 1.04 | 0.016 |
Male gender | 1.73 | 1.21 - 2.53 | 0.004 | 2.31 | 1.44 – 3.78 | < 0.001 |
R.E.N.A.L nephrometry score | 1.38 | 1.22 - 1.55 | < 0.001 | 1.17 | 1.02 – 1.35 | 0.022 |
Adverse radiologic features | 5.32 | 3.82 - 7.42 | < 0.001 | 1.58 | 1.58 – 4.3 | < 0.001 |
Tumor size (max diameter) on pre-op imaging | 1.95 | 1.56 – 2.44 | < 0.001 | 2.6 | 1.17 – 2.16 | 0.003 |
BMI | 1.02 | 0.99 – 1.05 | 0.2 | Excluded from multivariable model | ||
Charlson comorbidity Index | 1.09 | 0.97 – 1.21 | 0.13 | Excluded from multivariable model |