Bcl-3 expression in DCs is required for IFN-γ production in response to T. gondii infection. (A) WT, Bcl-3−/−, and Bcl-3-∆-DC mice were infected with T. gondii and IFN-γ was measured in serum from infected animals 7 days p.i. Mean ± SEM; n = 14 mice/group pooled from 2 experiments. (B) Measurement of % infected cells in the peritoneal cavity of infected mice. Mean ± SEM; n = 6 mice/group pooled from 2 experiments. (C) Levels of IL-12p70 and IL-12-p40 in serum were assessed by ELISA 5 and 7 days p.i. Data are shown as mean ± SEM for n = 6 mice/group, pooled from 2 experiments. *p<0.05, **p<0.01, ***p<0.0001, unpaired, two-tailed Student’s t-test.