Number of patients with cholera admitted to cholera treatment facilities in Uvira
(A) Represents study period 1. (B) Represents study period 2. (A) and (B) show the cumulative number of confirmed cases in each study period by neighbourhood (ie, avenue) across the city, with the locations of the two health facilities where patients were recruited. There were 14 patients with cholera living in neighbourhoods of Uvira not included in the official map borders who were not included in study period 2. The second outbreak (ie, study period 2) started in the northern part of the city and spread to a refugee camp where many residents were admitted to the CTC but not included in the study as they were not living in Uvira at the time of vaccination. (C) Shows the epidemic curve of patients with suspected and confirmed cholera admitted to the CTC at the Uvira General Referral Hospital and the CTU at the Kalundu CEPAC health centre. Cholera was confirmed by culture or PCR in study period 1, and by alkaline peptone water-enriched rapid diagnostic test and culture in study period 2. Among the 183 individuals with suspected cholera who were detected before study period 1, 146 (79·8%) were tested for Vibrio cholerae O1 by enriched rapid diagnostic test with 37 (25·3%) testing positive. CTC=cholera treatment centre. CTU=cholera treatment unit. KOCV=killed whole-cell oral cholera vaccine.