Why carry out this study?

The prevalence of diabetes during pregnancy has increased in recent years, and many women with this complication require insulin during their pregnancy. Despite this, there remains a paucity of well-designed clinical trials targeting insulin use in this unique population

This systematic literature review aimed to assess and summarize the current body of evidence for insulin use in pregnant women with gestational or pre-existing diabetes and its effects on clinical, maternal and fetal outcomes

What was learned from the study?

This SLR included a total of 108 unique studies, both clinical and observational, and the most commonly reported outcomes were fasting blood glucose, method of delivery and large for gestational age

Overall, the results of this review revealed that the outcomes evaluated in studies investigating the use of insulin as a treatment option for pregnant women with diabetes varied widely across the included studies, illustrating the need for standardization of study design and outcome metrics