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. 2024 Apr 24;15:3463. doi: 10.1038/s41467-024-47556-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a–e Scatterplots displaying the relationship between levels of N- and S-specific antibodies across five rounds of measurement. Known vaccination status of each participant indicated by colors, cutoff levels indicated by dashed lines and percentages of people per category annotated in red. f–g Antibody levels over time between end of 2020 and April 2022. The observations are indicated by circles and the trend is indicated via smoothing splines constructed on the basis of these data. Source data are provided as a Source Data file.