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Proteomics workflow, data collection, and analysis. Mice were infected with LCMV clone 13 virus at day 0 and sacrificed at 1 week, 8 weeks, and 28 weeks. Retina, RPE/choroid, kidney, and spleen were harvested and subjected to proteomic analysis by TMT labeling and subsequent nano-liquid chromatography–tandem mass spectrometry. Validation of selected protein changes was performed by single reaction monitoring. Created with Biorender.com.
