Table 4.
RPE/choroid and disease or function annotations at 8 weeks of LCMV infection.
Disease or function annotation | p-value | Predicted activation state | Activation z-score | No. of molecules |
---|---|---|---|---|
Electrophysiology of eye | 1.56E-08 | 30 | ||
Formation of eye | 1.63E-08 | −0.332 | 80 | |
Degeneration of eye | 3.64E-08 | Increased | 4.022 | 68 |
Retinal degeneration | 5.26E-08 | Increased | 4.022 | 67 |
Abnormal morphology of retina | 9.26E-08 | 42 | ||
Abnormal morphology of eye | 1.62E-07 | 56 | ||
Morphology of eye | 6.06E-07 | 61 | ||
Morphology of retina | 8.33E-07 | 44 | ||
Electrophysiology of retinal rods | 2.10E-06 | 18 | ||
Morphology of eye cells | 1.04E-05 | 30 | ||
Degeneration of photoreceptors | 1.32E-05 | Increased | 2.763 | 24 |
Morphology of retinal cells | 1.52E-05 | 27 | ||
Function of retina | 2.40E-05 | Decreased | −2.400 | 17 |
Function of retinal cells | 5.04E-05 | −1.951 | 15 | |
Hereditary retinal disease | 5.07E-05 | 41 | ||
Hereditary retinal degeneration | 6.03E-05 | 39 | ||
Morphology of photoreceptors | 7.42E-05 | 24 | ||
Development of retina | 1.31E-04 | 17 | ||
Abnormal morphology of photoreceptors | 1.63E-04 | 22 | ||
Progressive retinal atrophy | 2.68E-04 | 27 | ||
Maintenance of photoreceptors | 2.89E-04 | 10 | ||
Abnormal electrophysiology of eye | 3.21E-04 | 16 | ||
Neovascularization of eye | 3.54E-04 | 0.750 | 18 |