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. 2024 Apr 11;15:1390419. doi: 10.3389/fphar.2024.1390419

TABLE 1.

Concentration of Vitamin C in different species according to conventional extraction method.

Species Plant part Extraction methods Ripening stages and vitamin C content References
Stage I (green, unripe, RSI); stage II (orange, half-ripe, RSII); stage III (red, fully ripe; RSIII)
R. arvensis rose hips with seeds Water extract of fresh and air-dried fruits (maceration with boiling distilled water, 10:1, v/m) RSIII: 0.13 mg/g dw in fresh fruits Nađpal et al. (2016)
RSIII: 0.23 mg/g dw
Methanol extract of fresh and air-dried rose hips maceration with 80% aqueous methanol (10:1, v/m) RSIII: 0.32 mg/g dw in fresh fruits Nađpal et al. (2016)
RSIII: 0.42 mg/g dw
Purée extract (boiled rosehips followed by sieving for seed and residues removal) RSIII: 0.22 mg/g dw Nađpal et al. (2016)
R. canina flesh 2 g sample diluted with MilliQ water (50 mL) following by filtration RSIII: 101.38 (mg/100 g dw) Demir et al. (2014)
rose hips with seeds Water extract of fresh and air-dried fruits (maceration with boiling distilled water, 10:1, v/m) RSIII: 1.96 mg/g dw, in fresh fruits Nađpal et al. (2016)
RSIII: 2.09 mg/g dw
Methanol extract of air-dried rose hips (maceration with 80% aqueous methanol (10:1, v/m) RSIII: 1.87 mg/g dw Nađpal et al. (2016)
Purée extract (boiled rosehips followed by sieving for seed and residues removal) and evaporation in vacuo (40°C) RSIII: 3.73 mg/g dw Nađpal et al. (2016)
whole fruit Powder sample extracted with metaphosphoric acid (1%, 10 mL) followed by filtration RSIII: 68.04 mg/100 g dw Barros et al. (2011)
dried fruits Dried fruits mixed with 2% solution of metaphosphoric acid, followed by filtration RSIII: 446–541 mg/100 g Ropciuc et al. (2011)
whole fruit Lyophilized samples mixed with metaphosphoric acid (5%) RSI: 18 mg/100 g Nojavan et al. (2008)
RSII: 175 mg/100 g
RSIII: 417.5 mg/100 g
Air-dried (15°C–20°C) samples mixed with meta phosphoric acid (5%) RSI: 3.0 mg/100 g Nojavan et al. (2008)
RSII: 34.0 mg/100 g
RSIII: 211.0 mg/100 g
flesh and seeds Freeze-dried samples mixed with meta phosphoric acid (5%), and extracted in an ultrasonic bath (5500 Hz, at 20°C, for 10 min) RSI: 1913–2060 mg/100 g Medveckienė et al. (2021)
RSII: 1529–1758 mg/100 g
RSIII: 1574 mg/100 g
whole fruit Lyophilized powder of rosehip using Folin–Ciocalteau method RSIII: 880 mg/100 mL Al-Yafeai et al. (2018)
R. dumalis whole fruit Macerate mixed with metaphosphoric acid (2%, 1:4, w/v) RSIII: 20–850 mg/100 g Uggla et al. (2003)
whole fruit Maceration with boiling water (1 h) of fresh and air-dried fruits followed by evaporation to dryness RSIII: 1.51 mg/g dw in fresh fruits Nađpal et al. (2018)
RSIII: 1.60 mg/g dw in dry fruits
whole fruit Maceration with methanol/water (4:1; 3 days) followed by evaporation to dryness RSIII: 1.49 mg/g dw in fresh fruits Nađpal et al. (2018)
RSIII: 1.55 mg/g dw in dry fruits
flesh 2 g sample diluted with MilliQ water (50 mL) following by filtration RSIII: 65.7–97.7 mg/100 g Demir et al. (2014)
whole fruit Lyophilized powder of rosehip mixed with deionized water (1:10); subsequently the solution mixed with sodium carbonate (2%, Na2CO3), and Folin–Ciocalteau reagent (50%) SIII: 864–943 mg/100 mL Ercisli (2007)
R. gallica flesh 2 g sample diluted with MilliQ water (50 mL) following by filtration RSIII: 160.3 mg/100 g Demir et al. (2014)
R. hirtissima flesh 2 g sample diluted with MilliQ water (50 mL) following by filtration RSIII: 136. 1 mg/100 g Demir et al. (2014)
R. rubiginosa whole fruit Macerate mixed with meta phosphoric acid (2%, 1:4, w/v) RSIII: 415–660 mg/100 g Uggla et al. (2003)
R. rugosa whole fruit Saponification (10% methanolic KOH), followed by extraction using meta-phosphoric acid (4.5%) RSI: 955 mg/100 g Al-Yafeai et al. (2018)
RSII: 1090 mg/100 g
RSIII:798 mg/100 g
R. pisiformis whole fruit Lyophilized powder of rosehip mixed with deionized water (1:10); subsequently the solution mixed with sodium carbonate (2%, Na2CO3), and Folin–Ciocalteau reagent (50%) RSIII:811 mg/100 mL Ercisli (2007)
R. pulverulenta whole fruit Lyophilized powder of rosehip mixed with deionized water (1:10); subsequently the solution mixed with sodium carbonate (2%, Na2CO3), and Folin–Ciocalteau reagent (50%) RSIII:923 mg/100 mL Ercisli (2007)
R.rugosa flesh and seeds Freeze-dried samples mixed with meta phosphoric acid (5%), and extracted in an ultrasonic bath (5500 Hz, at 20°C, for 10 min) RSI: 2826–3036 mg/100 g Medveckienė et al. (2021)
RSII: 2261–2410 mg/100 g
RSIII:2235 mg/100 g
Rosa rugosa cv ‘Rubra’ flesh Freeze-dried samples mixed with meta phosphoric acid (5%), and extracted in an ultrasonic bath (5500 Hz, at 20°C, for 10 min) RSI: 1857–1996 mg/100 g Medveckienė et al. (2021)
RSII: 1816–1839 mg/100 g
RSIII:2095 mg/100 g
Rosa rugosa cv ‘Alba’ flesh Freeze-dried samples mixed with meta phosphoric acid (5%), and extracted in an ultrasonic bath (5500 Hz, at 20°C, for 10 min) RSI: 1751–1846 mg/100 g Medveckienė et al. (2021)
RSII: 1405–1613 mg/100 g
RSIII:1312 mg/100 g
R. sempervirens whole fruit Maceration with boiling water (1 h) of fresh and air-dried fruits followed by evaporation to dryness RSIII: 1.71 mg/g dw in fresh fruits Nađpal et al. (2018)
RSIII: 2.12 mg/g dw in dry fruits
whole fruit Maceration with methanol/water (4:1; 3 days) followed by evaporation to dryness RSIII: 1.49 mg/g dw in fresh fruits Nađpal et al. (2018)
RSIII: 1.58 mg/g dw in dry fruits
R. villosa whole fruit Lyophilized powder of rosehip mixed with deionized water (1:10); subsequently the solution mixed with sodium carbonate (2%, Na2CO3), and Folin–Ciocalteau reagent (50%) RSIII:727 mg/100 mL Ercisli (2007)
whole fruit Macerate mixed with metaphosphoric acid (2%, 1:4, w/v) RSIII: 205–415 mg/100 g Uggla et al. (2003)