Table 4.
Pregnancy outcomes—Cox proportional hazard models
| GLP1-RA group vs diabetic reference group | GLP1-RA group vs overweight/obese reference group | |||
| HR (95% CI) | HRadj (95% CI)* | HR (95% CI) | HRadj (95% CI)* | |
| Pregnancy loss† | 1.10 (0.65 to 1.89) | 1.67 (0.93 to 3.01) | 0.92 (0.56 to 1.49) | 0.80 (0.48 to 1.33) |
| Pregnancy termination‡ | 2.92 (1.18 to 7.20) | 3.89 (1.48 to 10.2) | 1.79 (0.89 to 3.62) | 1.39 (0.66 to 2.93) |
*Adjusted for maternal age, tobacco use, folate intake, past abortion or termination history.
†Spontaneous abortions and stillbirths.
‡Elective or medical termination of pregnancy.
GLP1-RA, glucagon-like peptide 1 receptor agonists; HRadj, adjusted HR.