Skip to main content
. 2024 Apr 17;18:100639. doi: 10.1016/j.resplu.2024.100639

Table 2.

Biomarkers on admission of successfully resuscitated OHCA patients.

Low IFABP (n = 25) High IFABP (n = 25) p value
Cytokines
 IL-6 (pg/mL) 26.9 [9.6–74.0] 100.7 [23.8–447.3] 0.004
 IL-8 (pg/mL) 12.1 [7.5–17.3] 58.3 [16.2–93.3] <0.001
 IL-1ra (pg/mL) 1213.5 [377–3961] 3533 [1500–9862] 0.02
Complement activation
 TCC (CAU/mL) 0.7 [0.4–2.2] 2.7 [1.0–4.7] 0.004
 C3bc (CAU/mL) 10.0 [6.4–16.0] 21.0 [13.0–57.0] 0.002
Platelet degranulation
 RANTES (pg/mL) 5926 [5026–6698] 7040 [5487–8289] 0.10
Endothelial injury
 Syndecan-1 (ng/mL) 21.6 [9.9–34.7] 30.8 [15.1–79.7] 0.05
 VE-Cadherin (ng/mL) 4055 (999) 3450 (1334) 0.08
 vWF (U/mL) 0.79 [0.49–1.747] 1.14 [0.66–1.88] 0.26

The cohort is divided by the median IFABP (31.4 ng/mL). Variables are expressed as mean (standard deviation) and compared by Student's t-Test, or median (interquartile range [Q1–Q3]) and compared by Wilcoxon rank-sum test. OHCA: Out-of-hospital cardiac arrest; IFABP: Intestinal Fatty Acid Binding Protein; IL: interleukin; RANTES: regulated on activation normal T-cell expressed and secreted; VE: vascular endothelial; U: Unit; vWF: von Willebrand factor; TCC: terminal complement complex; C3bc: activated complement C3.