Table 2.
Low IFABP (n = 25) | High IFABP (n = 25) | p value | |
---|---|---|---|
Cytokines | |||
IL-6 (pg/mL) | 26.9 [9.6–74.0] | 100.7 [23.8–447.3] | 0.004 |
IL-8 (pg/mL) | 12.1 [7.5–17.3] | 58.3 [16.2–93.3] | <0.001 |
IL-1ra (pg/mL) | 1213.5 [377–3961] | 3533 [1500–9862] | 0.02 |
Complement activation | |||
TCC (CAU/mL) | 0.7 [0.4–2.2] | 2.7 [1.0–4.7] | 0.004 |
C3bc (CAU/mL) | 10.0 [6.4–16.0] | 21.0 [13.0–57.0] | 0.002 |
Platelet degranulation | |||
RANTES (pg/mL) | 5926 [5026–6698] | 7040 [5487–8289] | 0.10 |
Endothelial injury | |||
Syndecan-1 (ng/mL) | 21.6 [9.9–34.7] | 30.8 [15.1–79.7] | 0.05 |
VE-Cadherin (ng/mL) | 4055 (999) | 3450 (1334) | 0.08 |
vWF (U/mL) | 0.79 [0.49–1.747] | 1.14 [0.66–1.88] | 0.26 |
The cohort is divided by the median IFABP (31.4 ng/mL). Variables are expressed as mean (standard deviation) and compared by Student's t-Test, or median (interquartile range [Q1–Q3]) and compared by Wilcoxon rank-sum test. OHCA: Out-of-hospital cardiac arrest; IFABP: Intestinal Fatty Acid Binding Protein; IL: interleukin; RANTES: regulated on activation normal T-cell expressed and secreted; VE: vascular endothelial; U: Unit; vWF: von Willebrand factor; TCC: terminal complement complex; C3bc: activated complement C3.