Table 2.

Treatment effect h of NTX-BUP vs. Placebo within and between race/ethnicity status.

	PHQ-9			TEA Total score			MA Craving
Racial and ethnic Subgroups	h(95% CI)	P-value‡	P-value†	h(95% CI)	P-value‡	P-value†	h(95% CI)	P-value‡	P-value†
Non-Hispanic White	-0.8 (1.9, 0.4)	0.77	Ref	3.1 (0.9, 5.3)	0.01	Ref	-9.3 (-14.7, −3.7)	<0.01	Ref
Non-Hispanic Black	-0.7 (-3.8, 2.4)	0.99	0.99	0.4 (-4.1, 4.9)	0.99	0.84	-13.5 (-26.5, −0.6)	0.16	0.99
Hispanic	-2.8 (-5.5, −0.1)	0.18	0.56	7.8 (2.5, 13.1)	0.01	0.32	-7.7 (-17.9, 2.4)	0.54	0.99
Non-Hispanic Other	-2.9 (-5.8, 0.0)	0.22	0.53	7.9 (2.8, 13.1)	0.00	0.25	-13.0 (-28.1, 2.1)	0.36	0.99

Note: ‡P-values are for mean change from baseline in treatment effect h within racial and ethnic subgroups and were adjusted for 4 multiple comparisons using the Bonferroni correction; †P-values are for comparisons in treatment effect h between racial and ethnic subgroups and were adjusted for 3 multiple comparisons using the Bonferroni correction