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. 2024 Apr 13;10(8):e29518. doi: 10.1016/j.heliyon.2024.e29518

Table 3.

In vitro anti-inflammatory (albumin denaturing potential) of crude extracts.

Conc (μg/mL) VASAQ VARAQ VARMEOH VASMEOH VARNHEX VASNHEX VASETOAC VARETOAC Diclofenac
50 5.78 ± 4.31 10.69 ± 3.77 6.93 ± 2.75 10.11 ± 4.75 45.95 ± 4.16 43.64 ± 1.32 42.19 ± 1.52 37.57 ± 1.00 a32.37 ± 1.50
100 10.11 ± 5.62 12.13 ± 4.25 14.16 ± 2.64 17.63 ± 1.80 48.55 ± 4.07 48.84 ± 1.04 43.93 ± 1.04 43.64 ± 3.04 a37.86 ± 1.26
200 12.13 ± 6.37 14.16 ± 2.00 17.63 ± 2.18 20.52 ± 2.52 50.00 ± 4.19 48.26 ± 0.76 45.37 ± 1.32 46.24 ± 3.12 a44.50 ± 0.86
300 19.94 ± 4.81 17.91 ± 0.57 21.67 ± 1.60 22.83 ± 2.00 50.28 ± 3.62 50.86 ± 0.57 53.17 ± 1.32 44.79 ± 2.08 a52.60 ± 4.73
400 28.61 ± 1.60 19.94 ± 0.76 28.32 ± 0.76 25.14 ± 2.31 52.89 ± 3.21 54.62 ± 1.15 54.62 ± 4.62 51.15 ± 1.75 a64.74 ± 0.76
IC50 ± SEM 1092.00 ± 4.10 17729.00 ± 2.04 1614.00 ± 2.18 4378.00 ± 2.00 192.90 ± 4.19 195.50 ± 0.57 233.80 ± 1.34 446.30 ± 2.08 214.40 ± 0.88

Expressed data are mean ± standard error of mean of determinations made in triplicate.

VASAQ – V. amygdalina aqueous extract (stem), VARAQ – V. amygdalina aqueous extract (root), VARMEOH – V. amygdalina methanol extract (root), VASMEOH – V. amygdalina methanol extract (stem), VARAHEX – V. amygdalina n-hexane extract (root), VASEHEX – V. amygdalina n-hexane extract (stem), VASETOAC – V. amygdalina ethylacetate extract (stem), VARETOAC – V. amygdalina ethylacetate extract (root).

a

- values at p < 0.05 are statistically significant.