. 2024 Apr 15;10(8):e29684. doi: 10.1016/j.heliyon.2024.e29684

Table 2.

Summary of meta-analysis results.

Phthalate	Cancer	Studies	Case (n)	Control (n)	Tests of association				Tests of heterogeneity
Phthalate	Cancer	Studies	Case (n)	Control (n)	Model	OR [95%CI]	Z	P-value	Q-value	P-value	I² (%)
MEP	Cancer	10	3011	6777	RE	1.026[0.790–1.332]	0.193	0.847	25.706	0.002	64.989
	Breast cancer	5	2437	4651	RE	0.982[0.696–1.387]	0.101	0.920	15.992	0.003	74.988
	Prostate cancer	2	180	1732	RE	0.887[0.253–3.104]	0.188	0.851	6.588	0.010	84.820
	Thyroid cancer	2	255	255	FE	1.301[0.828–2.045]	1.142	0.253	1.731	0.188	42.232
MnBP	Cancer	10	3011	6777	RE	0.958[0.711–1.290]	0.281	0.779	32.424	<0.001	72.242
	Breast cancer	5	2437	4651	FE	0.917[0.781–1.077]	1.054	0.292	4.453	0.348	10.179
	Prostate cancer	2	180	1732	FE	1.322[0.855–2.046]	1.255	0.210	0.248	0.618	0.000
	Thyroid cancer	2	255	255	RE	0.597[0.070–5.056]	0.473	0.636	20.08	<0.001	95.020
MEHP	Cancer	10	3011	6777	RE	1.286[0.953–1.736]	1.647	0.099	31.661	<0.001	71.574
	Breast cancer	5	2437	4651	FE	0.983[0.831–1.162]	0.203	0.839	2.445	0.654	0.000
	Prostate cancer	2	180	1732	FE	1.223[0.784–1.908]	0.203	0.839	2.445	0.654	0.000
	Thyroid cancer	2	255	255	RE	5.235[0.549–49.890]	1.439	0.150	12.974	<0.001	92.292
MBzP	Cancer	9	2900	6666	RE	0.824[0.668–1.017]	1.806	0.071	14.862	0.062	46.170
	Breast cancer	5	2437	4651	FE	0.731[0.626–0.854]	3.947	<0.001	3.365	0.499	0.000
	Prostate cancer	2	180	1732	FE	1.493[0.976–2.284]	1.847	0.065	1.239	0.266	19.315
MCHP	Cancer	2	1132	2606	RE	0.866[0.449–1.670]	0.429	0.668	4.962	0.026	79.845
MCPP	Cancer	5	1505	5197	RE	0.911[0.582–1.427]	0.407	0.684	17.982	0.001	77.755
MCPP	Breast cancer	4	1405	3621	RE	0.758[0.544–1.055]	1.641	0.101	6.405	0.093	53.164
MEHHP	Cancer	10	3011	6777	RE	1.407[1.021–1.940]	2.087	0.037	42.02	<0.001	78.582
	Breast cancer	5	2437	4651	FE	1.011[0.866–1.180]	0.133	0.895	2.593	0.628	0.000
	Prostate cancer	2	180	1732	RE	1.577[0.502–4.959]	0.780	0.435	6.798	0.009	85.290
	Thyroid cancer	2	255	255	RE	4.080[1.126–14.782]	2.141	0.032	6.259	0.012	84.022
MEOHP	Cancer	10	3011	6777	RE	1.217[0.958–1.547]	1.608	0.108	23.057	0.006	60.967
	Breast cancer	5	2437	4651	FE	0.953[0.818–1.111]	0.613	0.540	2.366	0.669	0.000
	Prostate cancer	2	180	1732	RE	1.721[0.876–3.380]	1.577	0.115	2.226	0.136	55.066
	Thyroid cancer	2	255	255	RE	2.098[0.868–5.071]	1.645	0.100	3.643	0.056	72.554
MiBP	Cancer	8	2756	6522	FE	1.024[0.882–1.189]	0.315	0.752	11.248	0.128	37.765
	Breast cancer	5	2437	4651	FE	0.968[0.882–1.140]	0.391	0.696	6.093	0.192	34.350
	Prostate cancer	2	180	1732	FE	1.229[0.800–1.889]	0.942	0.346	1.432	0.232	30.143
MECPP	Cancer	8	2824	4669	RE	1.428[1.021–1.997]	2.080	0.038	28.783	<0.001	75.680
	Breast cancer	4	2394	2687	RE	1.075[0.829–1.394]	0.545	0.586	6.425	0.093	53.307
	Prostate cancer	2	180	1732	FE	1.582[1.017–2.459]	2.036	0.042	0.765	0.382	0.000
DEHP	Cancer	7	1581	5352	RE	1.391[0.918–2.108]	1.557	0.120	23.381	0.001	74.338
	Breast cancer	4	1262	3481	RE	1.113[0.758–1.633]	0.545	0.586	6.886	0.076	56.432
	Prostate cancer	2	180	1732	RE	2.194[0.781–6.160]	1.492	0.136	5.147	0.023	80.572
DBP	Cancer	3	648	1058	FE	1.436[1.048–1.968]	2.249	0.025	0.459	0.795	0.000
DBP	Breast cancer	2	509	919	FE	1.389[0.990–1.950]	1.902	0.057	0.194	0.659	0.000
MMP	Cancer	4	1395	1469	RE	0.976[0.543–1.753]	0.083	0.934	12.61	0.006	76.209
MEHP%	Cancer	2	1176	1174	FE	1.136[0.888–1.454]	1.015	0.310	1.823	0.177	45.135
MCNP	Cancer	2	1129	1436	RE	0.986[0.594–1.637]	0.054	0.957	2.188	0.139	54.293
MCNP	Breast cancer	2	1129	1436	RE	0.986[0.594–1.637]	0.054	0.957	2.188	0.139	54.293
Total phthalates	Cancer	3	272	2184	FE	0.905[0.587–1.397]	0.449	0.653	1.320	0.517	0.000
Total phthalates	Breast cancer	2	133	2045	FE	0.746[0.428–1.302]	1.031	0.303	0.140	0.708	0.000

RE, random-effects model; FE, fixed-effects model.