Table 2. Effect of 17β-Estradiol Supplementation for 6 Weeks on General Characteristics of Mice after Surgery (Means ± SD)a.
sham | OVX | E2 | |
---|---|---|---|
initial body weight (g) | 20.67 ± 0.58 | 20.02 ± 0.26 | 20.60 ± 0.32 |
after surgery body weight (g) | 22.15 ± 0.81*** | 25.16 ± 0.77 | 24.56 ± 0.87 |
final body weight (g) | 25.28 ± 0.16*** | 28.70 ± 1.48 | 27.44 ± 1.92 |
uterus weight (g) | 0.18 ± 0.03**** | 0.03 ± 0.02 | 0.08 ± 0.01*** |
liver weight (g) | 1.25 ± 0.08 | 1.24 ± 0.05 | 1.24 ± 0.08 |
SC-WAT (g) | 0.27 ± 0.09**** | 0.76 ± 0.05 | 0.50 ± 0.14** |
PM-WAT (g) | 0.48 ± 0.07**** | 1.52 ± 0.24 | 0.84 ± 0.29** |
**p < 0.01,***p < 0.001, ****p < 0.0001 OVX versus sham or E2. SC-WAT, subcutaneous white adipose tissue; PM-WAT, parametrial white adipose tissue; sham, sham-operated mice; OVX, ovariectomized mice; and E2, ovariectomized mice that received twice-weekly supplementation of 17β-estradiol.