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. 2024 Apr 9;9(16):18212–18223. doi: 10.1021/acsomega.3c10399

Table 2. Effect of 17β-Estradiol Supplementation for 6 Weeks on General Characteristics of Mice after Surgery (Means ± SD)a.

  sham OVX E2
initial body weight (g) 20.67 ± 0.58 20.02 ± 0.26 20.60 ± 0.32
after surgery body weight (g) 22.15 ± 0.81*** 25.16 ± 0.77 24.56 ± 0.87
final body weight (g) 25.28 ± 0.16*** 28.70 ± 1.48 27.44 ± 1.92
uterus weight (g) 0.18 ± 0.03**** 0.03 ± 0.02 0.08 ± 0.01***
liver weight (g) 1.25 ± 0.08 1.24 ± 0.05 1.24 ± 0.08
SC-WAT (g) 0.27 ± 0.09**** 0.76 ± 0.05 0.50 ± 0.14**
PM-WAT (g) 0.48 ± 0.07**** 1.52 ± 0.24 0.84 ± 0.29**
a

**p < 0.01,***p < 0.001, ****p < 0.0001 OVX versus sham or E2. SC-WAT, subcutaneous white adipose tissue; PM-WAT, parametrial white adipose tissue; sham, sham-operated mice; OVX, ovariectomized mice; and E2, ovariectomized mice that received twice-weekly supplementation of 17β-estradiol.