. Author manuscript; available in PMC: 2024 Apr 25.

Published in final edited form as: Immunol Rev. 2022 Jul 8;312(1):76–102. doi: 10.1111/imr.13107

TABLE 4.

Categorizing isolation methods based on EV recovery

Isolation method	% yield
Precipitation	90	111,125–127,129–133
Size exclusion chromatography (SEC)	40–90
Ultrafiltration (UF)	10–80
Differential centrifugation (DC)	2–80
Density gradient centrifugation (DGC)	10
Immunocapture assays (ICA)