Table 1 –
MicroRNA profile change associated with development of TAAs.
| MicroRNA | Elastase (TAA) | Sham | Fold change | P value |
|---|---|---|---|---|
| mmu-miR-466j | 4.27 | 1.37 | 7.5 | 0.000321 |
| mmu-miR-669m-5p | 4.2 | 1.75 | 5.47 | 0.048789 |
| mmu-miR-466m-5p | 4.2 | 1.75 | 5.47 | 0.048789 |
| mmu-miR-7030-5p | 5.78 | 3.37 | 5.3 | 0.002533 |
| mmu-miR-16-1-3p | 5.13 | 2.86 | 4.81 | 0.015729 |
| mmu-miR-466f-5p | 3.77 | 1.83 | 3.83 | 0.013445 |
| mmu-miR-669f-5p | 4.79 | 2.85 | 3.82 | 0.005678 |
| mmu-miR-146a-5p | 10.36 | 8.43 | 3.81 | 0.001597 |
| mmu-miR-297a-5p | 3.56 | 1.95 | 3.04 | 0.014395 |
| mmu-miR-184-3p | 2.61 | 1.06 | 2.92 | 0.034604 |
| mmu-miR-298-5p | 3.82 | 2.27 | 2.91 | 0.026738 |
| mmu-miR-675-3p | 2.36 | 0.95 | 2.67 | 0.000908 |
| mmu-miR-21a-3p | 2.83 | 1.48 | 2.54 | 0.024625 |
| mmu-miR-466c-5p | 2.59 | 1.36 | 2.36 | 0.000456 |
| mmu-miR-7242-5p | 2.55 | 1.32 | 2.34 | 0.006377 |
| mmu-mir-466f-1 | 3.01 | 1.8 | 2.32 | 0.023617 |
| mmu-miR-466i-5p | 3.38 | 2.18 | 2.29 | 0.014127 |
| mmu-miR-3082-5p | 2.66 | 1.51 | 2.22 | 0.000485 |
| mmu-miR-3113-5p | 2.09 | 0.96 | 2.19 | 0.027791 |
| mmu-miR-6366 | 10.69 | 9.59 | 2.15 | 0.047585 |
| mmu-miR-3470b | 5.13 | 4.03 | 2.14 | 0.024054 |
| mmu-miR-296-3p | 4.38 | 3.29 | 2.13 | 0.012443 |
| mmu-miR-211-3p | 8.63 | 7.59 | 2.05 | 0.022572 |
| mmu-miR-431-3p | 2.05 | 1.03 | 2.03 | 0.004913 |
| mmu-mir-7017 | 2.66 | 1.65 | 2.01 | 0.049597 |
| mmu-miR-27b-3p | 10.73 | 11.74 | −2.01 | 0.017931 |
| mmu-miR-135a-1-3p | 5.32 | 6.33 | −2.01 | 0.029722 |
| mmu-miR-29c-5p | 1.39 | 2.43 | −2.06 | 0.025172 |
| mmu-miR-30e-5p | 6.41 | 7.46 | −2.07 | 0.035031 |
| mmu-miR-193b-3p | 9.98 | 11.06 | −2.11 | 0.034595 |
| mmu-miR-30b-5p | 8.97 | 10.07 | −2.15 | 0.037288 |
| mmu-miR-6402 | 1.07 | 2.18 | −2.17 | 0.00896 |
| mmu-miR-29b-2-5p | 3.74 | 4.87 | −2.18 | 0.037587 |
| mmu-miR-28c | 4.39 | 5.57 | −2.28 | 0.009741 |
| mmu-miR-330-5p | 1.06 | 2.27 | −2.32 | 0.009426 |
| mmu-let-7g-5p | 8.67 | 9.89 | −2.33 | 0.047137 |
| mmu-miR-143-5p | 6.22 | 7.46 | −2.36 | 0.035235 |
| mmu-miR-30c-5p | 10.08 | 11.33 | −2.39 | 0.016775 |
| mmu-miR-30c-2-3p | 5.04 | 6.32 | −2.42 | 0.030918 |
| mmu-miR-193b-5p | 4.62 | 5.93 | −2.48 | 0.046162 |
| mmu-miR-224-3p | 2.03 | 3.35 | −2.49 | 0.011135 |
| mmu-miR-140-5p | 8.54 | 10 | −2.75 | 0.00921 |
| mmu-miR-26b-5p | 4.27 | 5.77 | −2.83 | 0.009411 |
| mmu-miR-486-5p | 8.51 | 10.13 | −3.08 | 0.008965 |
| mmu-miR-3107-5p | 8.51 | 10.13 | −3.08 | 0.008965 |
| mmu-miR-224-5p | 1.39 | 3.05 | −3.16 | 0.034512 |
| mmu-miR-187-3p | 6.44 | 8.17 | −3.33 | 0.0044 |
| mmu-miR-486-3p | 3.11 | 4.94 | −3.57 | 0.021334 |
| mmu-miR-451a | 6.09 | 8.43 | −5.06 | 0.04488 |
| mmu-miR-133b-3p | 4.9 | 7.32 | −5.35 | 0.007351 |
| mmu-miR-29c-3p | 4.52 | 6.98 | −5.5 | 0.005186 |
| mmu-miR-24-1-5p | 2.41 | 4.98 | −5.92 | 0.002812 |
| mmu-miR-133a-3p | 5.4 | 8.17 | −6.78 | 0.004342 |
Highlighted miRNAs represent the important miRs that regulate vascular inflammation.