Table 3. Agreement of MSI status in validation cohort from four laboratories.

	MSS (Agreement %)	MSI-L (Agreement %)	MSI-H (Agreement %)	Cohen’s Kappa [95% CI]
Paired
Laboratory 2	21/22 (95.5)	0/2 (0)	6/6 (100)	0.7443 [0.4822; 1.000]
Laboratory 3	20/20 (100)	0/1 (0)	10/10 (100)	0.9297 [0.7974; 1.000]
Laboratory 4	13/14 (92.8)	1/5 (20)	11/11 (100)	0.7175 [0.5081; 0.9270]
Laboratory 5	23/23 (100)	0/3 (0)	10/10 (100)	0.8194 [0.6350; 1.000]
Universal
Laboratory 2	21/22 (95.5)	0/2 (0)	6/6 (100)	0.7443 [0.4822; 1.000]
Laboratory 3	20/20 (100)	0/1 (0)	10/10 (100)	0.9297 [0.7974; 1.000]
Laboratory 4	14/14 (100)	0/5 (0)	11/11 (100)	0.7076 [0.5036; 0.9116]
Laboratory 5	23/23 (100)	0/3 (0)	10/10 (100)	0.8194 [0.6350; 1.000]