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Mice deficient in CD4+ or CD8+ T cells demonstrate higher pro-inflammatory macrophages and neutrophils and lower anti-inflammatory macrophages. Flow cytometry analysis from peri-implant bone marrow at 14 days post-implantation (n=6). p<0.05: A vs. WT, B vs. Cd4−/−, # vs. smooth Ti, $ vs. rough Ti.
