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. 2024 Apr 14;30(14):2038–2058. doi: 10.3748/wjg.v30.i14.2038

Figure 7.

Figure 7

Inflammatory response in hM3/Ptf1α(cre) transgenic animal models consistent with the caerulein model. hM3/Ptf1α(cre) model and its pathological images with inflammatory gene validation. A: Schematic representation of the hM3/Ptf1α(cre) model; B: H&E staining of pancreatic tissue schematic representation of the modeling methods; C-K: Validation of the significant differentially expressed genes in the transgenic animal hM3/Ptf1α(cre) model after inducing acute pancreatitis, which were found in the NOD-like receptor and TLR signaling pathways. n = 6 per group, aP < 0.01, bP < 0.001. CON: Control; CNO: Clozapine N-oxide.